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Serum Myostatin as a Biomarker of the Restoration of Disused Skeletal Muscle Research Completed
Title
Serum Myostatin as a Biomarker of the Restoration of Disused Skeletal Muscle
Lead Author
Heather K Smith
Organisation(s)
Prepared for Sport and Recreation New Zealand by University of Auckland
We evaluated the validity and biological meaningfulness of the measurement of myostatin protein in blood using surface plasmon resonance (SPR), with regard to its potential use in the monitoring of the restoration of disused skeletal muscle by exercise. Levels of myostatin in serum are measurable by SPR, but the lack of a significant relation between serum myostatin and either muscle myostatin or changes in muscle use indicate limited usefulness as a biomarker for the restoration of muscle mass.
